Kris Carlson

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Koan

Zhaozhou asked Touzi, “When one has died the great death in what fashion does he return to earth?”
Touzi said, “He must return in broad daylight.”

–Quoted in Cleary, Meditating with Koans

October 9, 2011 Posted by | Zen | , , , , , | Leave a comment

Koan

A monk asked Yunmen, “What is pure Dharmakaya?”
Yunmen said, “A flowering hedge.”

October 9, 2011 Posted by | Zen | , , , , | Leave a comment

Koan

Heshan imparted this saying: “Practicing and studying is called ‘learning.’ Being at the end of your studies is called ‘being close.’ Going beyond these two is real going beyond.”
A monk came forward and asked, “What is real going beyond.”
Heshan said, “Knowing how to beat the drum.”
The monk asked, “What is the real truth?”
Heshan said, “Knowing how to beat the drum.”
The monk asked, “When a transcendant being comes, how to you receive him?”
Heshan said, “Knowing how to beat the drum.”
–Quoted in Cleary, Meditating with Koans

October 9, 2011 Posted by | Zen | , , , , | Leave a comment

Koan

A monk said to Zhaozhou, “I have just entered the Zen community and I request you to instruct me, Master.”
Zhaozhou said, “Have you eaten yet?”
The monk said, “I have.”
Zhaozhou said, “Then go wash your bowl.”

October 9, 2011 Posted by | Zen | , , , , | Leave a comment

Koan

Yangshan dreamt that he went to Maitreya Buddha’s house and occupied the third seat in the assembly. A venerable one pounded the gavel and said, “Today the one in the third seat will expound the Dharma.”
Yangshan stood, pounded the gavel, and said, “The Dharma of the Great Vehicle is beyond all the permutations of affirmation and denial. Listen carefully!”
–Quoted in Cleary, Meditating with Koans

October 9, 2011 Posted by | Zen | , , , | Leave a comment

Koan

Fayan pointed to a screen. Two monks went to roll it up. Fayan said, “One gains, one loses.”
–Quoted in Cleary, Meditating with Koans

October 9, 2011 Posted by | Zen | , , , | Leave a comment

Koan

Wuzu said, “When you meet a person who has consummated the Path, do not answer him with words or silence. With what, then, do you reply?”
–Quoted in Cleary, Meditating with Koans

October 9, 2011 Posted by | Zen | , , , | Leave a comment

Koan

I see the slate is blank.
Now I realize it is upside down.

October 9, 2011 Posted by | Zen | | Leave a comment

Cancer control through apoptosis control

A problem for efficacious gene therapy has been identifying the control region for the gene to be transferred along with the gene. Here they not only identified a control region, bax, of the target gene, survivin, but mutated it to increase downregulation of the target, which is only expressed in developmental cells and consequently is ideal for cancer treatment. Survivin is an apoptosis inhibitor, so downregulating it allows the cancer cell-killing pathways to become active.

“The survivin protein is expressed highly in most human tumours and fetal tissue, but is completely absent in terminally differentiated cells.[3] This fact therefore makes survivin an ideal target for cancer therapy as cancer cells are targeted while normal cells are left alone.” (Wikipedia citing Sah NK, Khan Z, Khan GJ, Bisen PS (December 2006). “Structural, functional and therapeutic biology of survivin”. Cancer Lett. 244 (2): 164–71.doi:10.1016/j.canlet.2006.03.007PMID 16621243)

http://ttc.nci.nih.gov/opportunities/opportunity.php?opp_id=601

IF bax works similarly in humans, this will be tried for suppression of brain tumors. Likewise, we could look for bax downregulation as a cause of cancer in aging humans.

http://www.ncbi.nlm.nih.gov/pubmed/16619663

November 3, 2010 Posted by | Biogerontology | , , , , , | Leave a comment

Recommended reading on the economy

Imprimis from Hillsdale College.

http://www.hillsdale.edu/news/imprimis.asp

& check the archives.

Thomas Sowell.

http://www.jewishworldreview.com/cols/sowell1.asp

http://www.tsowell.com/

Here’s a great paraphrase of an economist on CSPAN, I believe.

‘One of the biggest causes of our current economic predicament is that we can’t easily choose from a competitive marketplace of money. To say all money should be based on gold is as bad as saying people don’t need a selection of fruits–apples, oranges, bananas–let’s just choose for them and make things simple.’

And money is a far more important product than fruit. If the government had to offer its money in a competitive marketplace, it would be forced to be more fiscally responsible.

October 22, 2010 Posted by | Economics | Leave a comment

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